Annique Forever Young Bo-Serum 30ml
A facelift in a bottle — South Africa’s first BoNT-L Peptide serum that visibly reduces wrinkles and relaxes the skin without injections or surgery.
What It Does
Expression lines and deep wrinkles form over time as a direct result of repeated facial movements — laughing, frowning, squinting and smiling all leave their mark on the skin. Over years, the skin develops a muscle memory of these repeated expressions, and the lines they create become increasingly difficult to address with conventional skincare. The Annique Rooibos Forever Young Bo-Serum was developed specifically to address this challenge.
Bo-Serum was the first skincare product in South Africa to contain the BoNT-L Peptide — a state-of-the-art wrinkle-reducing peptide that works by relaxing the skin so that the muscle memory of the wrinkle is gradually lost and the skin remains smoother for longer. It is a safe, non-invasive and non-toxic approach to achieving results that were previously only possible through injections or surgery — without the risk, the toxicity or the loss of natural expression.
The results are both immediate and progressive. On first application users can see visible firmness and instant smoothness — as if lifted. With consistent use over 28 days, a marked improvement in lines, wrinkles and skin dryness becomes apparent. At three months of regular use, results are at their optimum — visibly smoother, more moisturised and more defined skin contours.
Alongside the BoNT-L Peptide, Cogon Grass Extract provides high potassium content that helps the skin transfer and retain moisture for up to 24 hours — keeping the skin hydrated, relaxed and more resistant to the formation of new lines. Rooibos Extract adds hypoallergenic and antioxidant protection throughout. Suitable for all skin types, usable from age 15 and effective even for men — this is one of Annique’s most remarkable and celebrated products.
Key Ingredients & Benefits
BoNT-L Peptide South Africa’s first cosmetic use of this advanced wrinkle-reducing peptide. The BoNT-L Peptide works by relaxing the skin and helping it lose the muscle memory of repeated expression lines — minimising deep wrinkles and furrows and keeping the skin smoother for longer with consistent use. It is non-toxic, non-invasive and contains peptides rather than toxins, making it a safe and effective alternative to injectable treatments.
Cogon Grass Extract A potassium-rich botanical extract with a high anti-wrinkle impact and long-lasting moisturising effect. Potassium plays a key role in helping the skin transfer and retain moisture more effectively — keeping the skin hydrated and moisturised for up to 24 hours. A well-moisturised, relaxed skin is significantly more resistant to the formation of new wrinkles and better able to maintain the smoothing effects of the BoNT-L Peptide over time.
Rooibos Extract (Aspalathus Linearis) Annique’s exclusive signature ingredient, included for its hypoallergenic and antioxidant properties. Rooibos soothes and calms reactive skin, protects against oxidative stress and free radical damage and ensures the formula is gentle enough for even the most sensitive skin types.
What It Improves
- Deep wrinkles and expression lines
- Skin firmness and definition of skin contours
- Skin hydration and long-lasting moisture retention
- Skin relaxation and stress response
- Prevention of new wrinkle formation from repeated facial expressions
Who It’s For
Those with expression lines and deep wrinkles Formulated specifically to address the lines and furrows caused by repeated facial expressions — frowning, smiling, squinting — that conventional anti-ageing products cannot effectively resolve.
Those wanting a non-invasive alternative to injections Bo-Serum delivers visible wrinkle-reducing results without the toxicity, risk or cost of injectable treatments — making it the ideal choice for those wanting effective results through safe, topical skincare.
From age 15 — preventative use Bo-Serum can be used from age 15 as a preventative treatment. By relaxing the skin early, it helps prevent the deep lines and furrows that form over years of repeated facial expression — particularly useful for those with a family history of deep expression lines.
Men Equally effective for male skin — Bo-Serum works for all skin types regardless of gender.
Those who have had facial surgery or Botox Safe to use alongside or following facial surgery or Botox therapy.
How To Use
- Cleanse skin thoroughly morning and evening with a suitable Annique cleanser.
- Apply Essense Skin Detox.
- Press Bo-Serum onto the face and neck — either as a zone treatment on specific wrinkles and expression lines, or across the full face, neck and bust area.
- Follow with Forever Young Revitalising Cream.
- Apply your preferred Annique moisturiser suited to your skin type.
- Use twice daily — morning and evening — for optimum results.
Pairs Well With
- Annique Essense Skin Detox
- Annique Forever Young Revitalising Cream
- Annique Forever Young Crème de Nuit
- Annique Forever Young Retinol Night Treatment
- Annique Forever Young Eye Therapy
- Annique Lucid Moisturiser Dry Skin
- Annique Lucid Freshener
Frequently Asked Questions
How does Bo-Serum compare to Botox? Botox is a medical substance administered by injection at a medical practitioner’s surgery. Bo-Serum contains peptides — not toxins — that simulate the skin-relaxing results of Botox without the toxicity, the injection or the loss of natural muscle control. It is non-toxic, non-dangerous and completely safe for home use as part of your daily skincare routine.
How quickly will I see results? An improvement in lines, furrows and dryness can be seen after 24 hours of first use. After 28 days of consistent use a marked improvement in lines, wrinkles and skin hydration becomes apparent. At three months of regular twice-daily use, results are at their optimum — visibly smoother, more moisturised and more defined skin.
Will my wrinkles return if I stop using Bo-Serum? Yes. If Bo-Serum is discontinued, the skin and muscles will gradually relearn the furrows and expression lines as facial movements continue. The timing of this varies by individual skin type and circumstances. Consistent, ongoing use is recommended to maintain results.
How is Bo-Serum different from the Forever Young Revitalising Cream? The Revitalising Cream nourishes and restores the skin — repairing damage, stimulating new cell production and preventing free radical damage. Bo-Serum specifically targets wrinkles caused by repeated facial expressions — relaxing the skin so the muscle memory of those lines is gradually lost. The two products work in complementary ways and are recommended for use together.
When in my routine should I apply Bo-Serum? Bo-Serum should be applied after Essense Skin Detox and before the Forever Young Revitalising Cream and moisturiser. Applying it early in the routine — before other treatment products — allows the skin to relax fully, helping the products that follow to function at their best. The Cogon Grass Extract also ensures the skin stays moisturised for longer, which helps the wrinkle-relaxing effect last throughout the day.
Can I use Bo-Serum on specific areas only? Yes. Bo-Serum can be used as a zone treatment — applied directly to specific expression lines such as frown lines, crow’s feet or forehead lines. It can also be applied across the full face, neck and bust for broader anti-wrinkle and moisturising benefits.
From what age can I use Bo-Serum? Bo-Serum can be used from age 15 as a preventative treatment. Looking at hereditary lines in parents and siblings can help identify where expression lines may form later in life — and targeted early application of Bo-Serum can help prevent those lines from developing.


Robynne Shields –
I absolutely love this product. Instant refreshed and tighter skin.